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63Dean RC, Lue TF Physiology of penile erection and pathophysiology of erectile dysfunction. Testosterone is the main hormone responsible for your sex drive, explains New York based urologist and sex expert David Shusterman, MD If it plummets, your desire to get going in the say may, too. This often causes the swelling of the foreskin that can lead to the blockage of the blood flow in the glans.
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