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As cGMP is naturally limited by PDE 5, L Arginiine s impact on the body is preserved and extended by the PDE 5 inhibitors in the formula, such as Long Jack and Horny Goat Weed. Plus, the estrogen in birth control can increase sex hormone binding globulin , which binds testosterone so that there s less of it circulating in the body, says Gunter. With all of the data and critical elements provided, we hope that you can select the supplement that best fits your needs.

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