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It is best to wait 7 full days after starting the pill to ensure you are protected before engaging in sexual intercourse. Wholesale Supplements are manufactured in UK and is using only the best pharmaceutical grade herbal ingredients ensuring our formulations are amongst the strongest in the market place today. The pharmacokinetics of sildenafil in patients with severe hepatic impairment has not been studied. Sildenafil and vardenafil should be taken on an empty stomach because lipids in foods can decrease and delay absorption126 tadalafil and avanafil are not as strongly affected by food127,128.

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