2024-12-31T08:06:03+0000

Originally, they were used to treat conditions such as high blood pressure and angina, but it was later discovered that they were also effective in treating the symptoms of ED. During normal sexual stimulation, cGMP is produced in the penis, where it causes the muscle in the spongy tissue of the penis to relax, allowing the flow of blood into the corpora, producing the erection. Saquinavir increases levels of sildenafil by affecting hepatic intestinal enzyme CYP3A4 metabolism. A starting dose of 25 mg of VIAGRA should be considered in patients taking erythromycin or strong CYP3A4 inhibitors. If your dose is different, do not change it unless your doctor tells you to do so.

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